Prevalence of genital chlamydia in Iranian males with urethritis attending clinics in Mashhad

Chlamydia trachomatis is a common cause of sexually transmitted disease which can cause severe consequences. Effective prevention requires knowledge of prevalence of infection in order to target interventions in a cost-effective manner. To determine the prevalence of chlamydial infection in Mashhad, northeastern Islamic Republic of Iran, this study was performed among male patients with urethritis. Urethral discharge was collected from 150 patients. Cell culture was established for diagnosis of Chlamydia in genital specimens. Cell culture showed that 9.3% of patients in this study were infected with Chlamydia. This study provides strong evidence that prevalence of Chlamydia in our region is quite high, which necessitates screening and treatment for the infection

Study of the sensitivity of neisseria gnorrhoeae to ciprofloxacin

Background and Purpose: Gnorrhoeae is one of the most common sexually transmitted diseases in the developing and developed countries. This bacterium has gained some resistance agaist several antibiotics used as promary medication in the past deccade; therefore, the use of ciprofloxacin has been recommended. On the basis of reportsd on the reducation of this bacterium to ciprofloxacin, this study in conducted to determine its sensitivity

Methods and Materials: This descriptive research was conducted on the population of patients admitted to medical laboratories in Mashad, Iran, who were suspicious of having Neisseria Gnorrhoeae. They were selected by convenient sampling. 1348 cases with urethral discharge were examined from 2003 to 2004; two swaps were taken for smear and culture. After colony growth and the identification of the Neisseria Gnorrhoeae, antibiogram was performed via disc diffusion with penicilin, tetracyclin, erythromycin, and ciprofloxacin discs. Then the minimal inhibitory concentration was deetermined for ciprofloxacin

Results: 71 cases of Neisseria Gnorrhoeae were identified, of which 16.9% were sensitive to penicilin, 25.3% to tetracyclin, 67.6% to erythromycin, and 70.3% to ciprofloxacin. 6 cases were resistant to ciprofloxacin and their MIC ranged from 1 to 16 microgr/ml

Conclusion: Since ciprofloxacin is currently the primary treatment for Neisseria Gnorrhoeae, it seems that with the increased resistance obsered in the present study, ciprofloxacin can no longer be considered as the preferred antibiotic against Neisseria Gnorrhoeae. Therefore, self treatment without medical prescription is strongly prohibited